VBIGenomeACS

"Genome Annotation and Comparison System", J.Zhao, T.Xue, B.Yang, K.Williams,A.R.Wattam,R.Will,B.Sharp,R.Kenyon,O.Crasta,B.W.Sobral

• Build with ToolBus/PathPort system which provide a generic Web Service framework to integrate backend data sources through a business logic layer
• Web Service and XML are the core technologies for an extensible, scalable and open standard based bioinformatics tool framework
• The system was designed to use a distributed architecture; consists of a central registration database and multiple satellite category databases
• Central registration database provides the URL of each different category of databases as well as an entry point for each segment accession identifier. All the category databases share the same database schema, allowing for the Web service to fetch a detailed annotation from any of the databases on-the-fly.
• Support for the annotation edition and version control was build into the database schema but the implementation of this feature is left as future work